1,2,4-Trihydroxybenzene (Standard)

Description

1,2,4-Trihydroxybenzene Hydroxyhydroquinone Standard is the analytical standard of 1,2,4-Trihydroxybenzene HY-W010451 . This product is intended for research and analytical applications. 1,2,4-Trihydroxybenzene Hydroxyhydroquinone is an ER stress inducer that targets proteins such as PKR-like ER kinase PERK to induce cytotoxicity. 1,2,4-Trihydroxybenzene selectively activates eIF2? phosphorylation, activates the PERK-eIF2? signaling pathway and induces stress granule formation. 1,2,4-Trihydroxybenzene subsequently exacerbates oxidative stress and causes DNA double-strand breaks, destroying organelles such as mitochondria and ER, and inducing cell death. 1,2,4-Trihydroxybenzene also has the potential to exhibit anti-tumor effect, increase blood pressure, and relieve spasm.