GENERAL CATALOGUE
1,8-Dihydroxy-4,5-dinitroanthraquinone
HY-121138 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-121138
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medchemexpress.com/1-8-dihydroxy-4-5-dinitroanthraquinone.ht...Catalog No: HY-121138
CAS No: 81-55-0
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
1,8-Dihydroxy-4,5-dinitroanthraquinone ARDP0006; DHDNE is a potent inhibitor of serine proteinase NS2B/3, the dengue viral protein. 1,8-Dihydroxy-4,5-dinitroanthraquinone has intermolecular proteinase activity and viral inhibition ability with IC50s of 432 ?M and 4.2 ?M, respectively. Meanwhile 1,8-Dihydroxy-4,5-dinitroanthraquinone inhibits NS2B/3 cleavage in BHK-21 cells at a dose ranging from 4.2 ?M to 432 ?M.
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