(+/-)11(12)-EET methyl ester

Description

AAasAasAA+/- 11 12 -EET methyl ester 11,12-EET-methyl ester is a methylated derivative of 11,12-epoxyeicosatrienoic acid 11,12-EET HY-130494 . AAasAasAA+/- 11 12 -EET methyl ester cannot induce ?-arrestin recruitment of the G protein-coupled receptor GPR132. AAasAasAA+/- 11 12 -EET methyl ester fails to enhance the expression of hematopoietic stem and progenitor cell HSPC markers. AAasAasAA+/- 11 12 -EET methyl ester can be used as a negative control molecule to study the structure-function relationship of 11,12-EET, facilitating the analysis of the role of the oxygenated fatty acid-GPR132 signaling axis in hematopoiesis.