GENERAL CATALOGUE
12(S)-HEPE
HY-W747548 · 25 g
MedChemExpress · Cat: HY-W747548
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medchemexpress.com/12-s-hepe.htmlCatalog No: HY-W747548
CAS No: 116180-17-7
Category: GPCR G Protein
Pack Size: 25 g
Brand: MedChemExpress
Description
12 S -HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12 S -HEPE to 12 S ,20-diHEPE, whereas stimulated neutrophils produce 5 S ,12 S -HEPE via the 5-lipoxygenase pathway. The competitive action of 12 S -HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ?-3 fatty acids.
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