

HY-124404A · 100 g
MedChemExpress · Cat: HY-124404A
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medchemexpress.com/12-s-hete.htmlDescription
12 S -HETE is the 12-lipoxygenase metabolite of arachidonic acid and has a mitogenic effect on cancer cell proliferation. 12 S -HETE induces tyrosine phosphorylation of cellular proteins, promotes ERK and P38 MAPK phosphorylation, increases DNA synthesis, and stimulates the proliferation of pancreatic cancer cells.





