GENERAL CATALOGUE
1400W Dihydrochloride
HY-18731 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-18731
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medchemexpress.com/1400W_Dihydrochloride.htmlCatalog No: HY-18731
CAS No: 214358-33-5
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
1400W dihydrochloride is the dihydrochloride form of 1400W HY-18730 . 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase iNOS inhibitor, with a Kd value ? 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation.
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