GENERAL CATALOGUE
15(S)-Latanoprost
HY-126115 · 1 mg
MedChemExpress · Cat: HY-126115
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Catalog No: HY-126115
CAS No: 145773-22-4
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
15 S -Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15 S -latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 ?g dose of 15 S -latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.