15(S)-Latanoprost (Standard)

Description

15 S -Latanoprost Standard is the analytical standard of 15 S -Latanoprost. This product is intended for research and analytical applications. 15 S -Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15 S -latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 ?g dose of 15 S -latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.