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17-Demethoxy-reblastatin
GENERAL CATALOGUE

17-Demethoxy-reblastatin

HY-164372 · 50 mg

MedChemExpress · Cat: HY-164372

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Catalog No: HY-164372
CAS No: 299173-64-1
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

17-Demethoxy-reblastatin 17-DR is an inhibitor for heat shock protein 90 Hsp90 , with an IC50 of 1.82 ?M for yeast Hsp90 ATPase. 17-Demethoxy-reblastatin inhibits the proliferation of cancer cell HepG2 and SMMC7721, reduces the colony formation, and induces apoptosis through mitochondria and caspase mediated pathway.

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