17-ODYA (Standard)

Description

17-ODYA Standard is the analytical standard of 17-ODYA. This product is intended for research and analytical applications. 17-ODYA is a CYP450 ?-hydroxylase inhibitor. 17-ODYA is also a potent inhibitor IC50<100 nM of the formation of 20-hydroxyeicosatetraenoic acid 20-HETE , epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids by rat renal cortical microsomes incubated with arachidonic acid. 17-ODYA completely attenuates the isoproterenol ISO -induced apoptosis, and necrosis in cultured cardiomyocytes 1 2 3 . 17-ODYA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition CuAAc with molecules containing Azide groups.