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2?,3?-Dideoxy-5-ethyluridine
GENERAL CATALOGUE

2?,3?-Dideoxy-5-ethyluridine

HY-116240 · 50 mg

MedChemExpress · Cat: HY-116240

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Catalog No: HY-116240
CAS No: 108895-49-4
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

2?,3?-Dideoxy-5-ethyluridine ddEtUrd is an antiretroviral compound with weak anti-HIV activity. The 3-substituted derivatives of 2?,3?-Dideoxy-5-ethyluridine did not show significant antiviral effects. 2?,3?-Dideoxy-5-ethyluridine was less potent in inhibiting HIV replication in human MT4 lymphocytes. Although phosphorylation induced by 2?,3?-Dideoxy-5-ethyluridine is essential for antiviral activity, there is no strong correlation between its affinity for human dThd kinase or dCyd kinase.

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