GENERAL CATALOGUE
2',3'-Dideoxycytidine, 98+%
L10619MF ·
Thermo Fisher Scientific · Cat: L10619MF
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Catalog No: L10619MF
CAS No: 7481-89-2
Category: Biochemical Reagents
Brand: Thermo Fisher Scientific
Description
2,3-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase Ki = 51 nM . It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered.