

HY-W010995 · 5 mg
MedChemExpress · Cat: HY-W010995
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/2-5-dimethylcelecoxib.htmlDescription
2,5-Dimethylcelecoxib is an analogue of celecoxib HY-14398 with anticancer activity but without COX-2 inhibitory activity. 2,5-Dimethylcelecoxib exerts its anti-cancer cell proliferation effect by inhibiting the core mechanism of the Wnt/?-catenin signaling pathway. 2,5-Dimethylcelecoxib also inhibits T-cell factor-dependent transcriptional activity and inhibits expression of the Wnt/?-catenin target gene products cyclin D1 and survivin.







