GENERAL CATALOGUE
2?-Deoxy-2?-fluoroadenosine
HY-W039442 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-W039442
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Manufacturer product page
medchemexpress.com/2-deoxy-2-fluoroadenosine.htmlCatalog No: HY-W039442
CAS No: 64183-27-3
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
2?-Deoxy-2?-fluoroadenosine is a fluorinated deoxyadenosine with antitumor and antiviral activity, able to interfere with viral or cancer cell replication by being incorporated into DNA. 2?-Deoxy-2?-fluoroadenosine can be used for the synthesis of 2?-Deoxy-2?-fluoro-modified oligonucleotides hybridized with RNA. 2?-Deoxy-2?-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase PNP to the toxic agent 2-fluoroadenine FAde . 2?-Deoxy-2?-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP.
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