2'-Deoxyguanosine monohydrate-13C5

Description

2-Deoxyguanosine monohydrate-13C5 is the 13C-labeled 2-Deoxyguanosine monohydrate HY-D0185 . 2-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer.