2-Deoxyuridine-1,2,3,4,5-13C5

Description

2-Deoxyuridine-1,2,3,4,5-13C5 is the 13C-labeled 2-Deoxyuridine HY-D0186 . 2AAasAasAa-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2-Deoxyuridine is a precursor in the synthesis of Edoxudine HY-B1011 and also an analogue of 5-ethynyl-2-deoxyuridine, EdU HY-118411 . 2AAasAasAa-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the A?25-35-induced brain injury, which is promising for research of AlzheimerAAasAasAas disease AD .