GENERAL CATALOGUE
2-Guanidinobezimidazole
HY-W158030 · 250 mg
MedChemExpress · Cat: HY-W158030
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medchemexpress.com/2-guanidinobezimidazole.htmlCatalog No: HY-W158030
CAS No: 5418-95-1
Category: Immunology Inflammation
Pack Size: 250 mg
Brand: MedChemExpress
Description
2-Guanidinobezimidazole is a selective agonist of NLRP3, with a KD value of 1.29 ?M to His-GFP-NLRP3. 2-Guanidinobezimidazole binds directly to the LRR domain of NLRP3, promoting inflammasome assembly and activation. 2-Guanidinobezimidazole promotes anti-tumor immunity, inhibits tumor growth, and overcome immune checkpoint blockade ICB resistance.
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