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2-MeS-ADP trisodium
GENERAL CATALOGUE

2-MeS-ADP trisodium

HY-108648 · 1 mg

MedChemExpress · Cat: HY-108648

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Catalog No: HY-108648
CAS No: 475193-31-8
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress

Description

2-Methylthioadenosine diphosphate trisodium is a potent purinergic P2Y receptors agonist, with EC50s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC50s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. 2-Methylthioadenosine diphosphate trisodium induces platelet aggregation and shape change, and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1.

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