GENERAL CATALOGUE
2-Thiouridine
HY-117813 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-117813
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Catalog No: HY-117813
CAS No: 20235-78-3
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses HCoV -229E, HCoV-OC43, SARS-CoV , and MERS-CoV.
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