

HY-125021 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-125021
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medchemexpress.com/2bact.htmlDescription
2BAct is a highly selective, and orally active eIF2B eukaryotic initiation factor 2B activator with an EC50 of 33 nM. 2BAct prevents neurological defects caused by a chronic integrated stress response. 2BAct is able to penetrate the central nervous system CNS . 2BAct displays improved solubility and pharmacokinetics relative to eIF2B activator ISRIB trans-isomer HY-12495 .