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3?,7?-Dihydroxy-5-cholestenoic acid
GENERAL CATALOGUE

3?,7?-Dihydroxy-5-cholestenoic acid

HY-W414824 · 50 mg

MedChemExpress · Cat: HY-W414824

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Catalog No: HY-W414824
CAS No: 1246298-66-7
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress

Description

3?,7?-Dihydroxy-5-cholestenoic acid is a C27 acid that displays elevated levels in Niemann-Pick type C and Niemann-Pick type B diseases, contributing to toxicity in oculomotor neurons. It is synthesized from 3?-hydroxy-7-oxocholest-5-en- 25R 26-oic acid 3?H,7O-CA through the enzymatic action of hydroxysteroid 11-? dehydrogenase 1.

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