3?-Azido-2?,3?-dideoxy-CTP

Name: 3?-Azido-2?,3?-dideoxy-CTP
Brand: MedChemExpress

HY-171574 · 50 mg

MedChemExpress · Cat: HY-171574

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Manufacturer product page

medchemexpress.com/3-azido-2-3-dideoxy-ctp.html

Catalog No: HY-171574

CAS No: 92562-77-1

Category: Anti-infection

Pack Size: 50 mg

Brand: MedChemExpress

Description

3?-Azido-2?,3?-dideoxy-CTP AZddCTP is a cytidine analog containing a 3-azido group. As a chain terminator, 3?-Azido-2?,3?-dideoxy-CTP can be incorporated into the nascent DNA chain by HIV reverse transcriptase. 3?-Azido-2?,3?-dideoxy-CTP terminates DNA synthesis due to the lack of a 3-hydroxyl group, thereby inhibiting viral replication. 3?-Azido-2?,3?-dideoxy-CTP has IC50 values of 15.6 ?M and 160.8 ?M for WT HIV and AZTR HIV. 3?-Azido-2?,3?-dideoxy-CTP has antiviral activity.