3-Deaza-2'-deoxyadenosine

Description

3-Deaza-2 -deoxyadenosine is a nucleoside analog synthesized from 2 -deoxyadenosine. 3-Deaza-2 -deoxyadenosine inhibits RNA synthesis by binding to ribose fragments of ribonucleotides, thereby preventing the formation of enzyme-substrate complexes, thereby preventing chain elongation, It can also inhibit DNA synthesis by binding deoxyribose fragments of DNA and preventing DNA polymerase from adding nucleotides to the growth chain. 3-Deaza-2 -deoxyadenosine has antiviral activity.