3-O-Methyltolcapone-d4

Description

3-O-Methyltolcapone-d4 Ro 40-7591 d4 is a deuterium labeled 3-O-Methyltolcapone HY-174062 . 3-O-Methyltolcapone Ro 40-7591 is a metabolite of Tolcapone HY-17406 . Tolcapone Ro 40-7592 is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits ?-syn and A?42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma.