(3aS,4R,9bR)-G-1

Description

3aS,4R,9bR -G-1 is a highly selective G protein-coupled receptor GPR30 GPER agonist with a Ki value of approximately 7 nM. 3aS,4R,9bR -G-1 activates rapid signaling pathways such as intracellular calcium mobilization and PI3K signaling through GPR30, promoting uterine epithelial cell proliferation and exerting antidepressant effects. 3aS,4R,9bR -G-1 is promising for research of breast cancer and depression.