

HY-15495B · 50 mg
MedChemExpress · Cat: HY-15495B
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medchemexpress.com/3s-tanzisertib-hydrochloride.htmlDescription
3S -Tanzisertib hydrochloride 3S -CC-930 hydrochloride is an orally active JNK inhibitor IC50 values for JNK1, JNK2, and JNK3 are 61, 7, and 6 nM, respectively . 3S -Tanzisertib hydrochloride selectively inhibits ERK1, p38?, and EGFR IC50 = 0.48, 3.4, and 0.38 ?M, respectively . 3S -Tanzisertib hydrochloride inhibits LPS-induced TNF? production in an acute rat PK-PD model. 3S -Tanzisertib hydrochloride can be used in idiopathic pulmonary fibrosis IPF research.







