GENERAL CATALOGUE
4-DAMP
HY-100958 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-100958
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Catalog No: HY-100958
CAS No: 1952-15-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
4-DAMP 4-DAMP methiodide is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil 5-Fu HY-90006 could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide LPS - and tobacco-induced pulmonary inflammation and reduces mucin 5AC MUC5AC , oligomeric mucus/gel-forming secretion.
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