GENERAL CATALOGUE
4-Hydroxy-Teriflunomide
CS-T-28773 ·
Clearsynth · Cat: CS-T-28773
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Catalog No: CS-T-28773
CAS No: 1058722-45-4
Category: Teriflunomide
Brand: Clearsynth
Description
4HydroxyTeriflunomide is a metabolite of Leflunomide , an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic Merck Index .