GENERAL CATALOGUE
?4 integrin receptor antagonist 3
HY-159179 · 50 mg
MedChemExpress · Cat: HY-159179
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Catalog No: HY-159179
CAS No: 863226-74-8
Category: Cytoskeleton
Pack Size: 50 mg
Brand: MedChemExpress
Description
?4 integrin receptor antagonist 3 Compound 11 is an orally active ?4integrin receptor antagonist. ?4 integrin receptor antagonist 3 can inhibit the adhesion of K562 cells mediated by the interaction between ?4?1/VCAM-1 and ?4?7/MAdCAM-1, with IC50 values of 130 nM and 2 nM, respectively. ?4 integrin receptor antagonist 3 has the potential to be used in the study of dextran sulfate sodium DSS colitis mouse model.
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