4-Methyl-1-phenyl-2-pentanone (Standard)

Description

Chlorpromazine hydrochloride Standard is the analytical standard of Chlorpromazine hydrochloride . This product is intended for research and analytical applications. Chlorpromazine hydrochloride is an orally active, blood-brain barrier-transparent antipsychotic agent that effectively antagonises D2 dopamine receptors and 5-HT2A, which is widely used in schizophrenia and other psychiatric disorders. Chlorpromazine hydrochloride exerts anti-cancer activity through a variety of pathways, including anti-proliferation, induction of autophagy and cycle arrest G2-M phase , inhibition of cytochrome c oxidase CcO , inhibition of tumour growth and metastasis, and inhibition of tumour immune escape. Chlorpromazine hydrochloride also blocks hNav1.7 channels IC50=25.9 ?M; concentration-dependent and HERG potassium channels IC50=21.6 ?M , which has potential for analgesic and cardiac arrhythmic studies. Chlorpromazine hydrochloride also can inhibit clathrin-mediated endocytosis.