4-Methylhistamine dihydrochloride

Description

4-Methylhistamine hydrochloride is the dihydrochloride salt of 4-Methylhistamine HY-W580721 . 4-Methylhistamine is a potent and selective agonist of histamine 4 receptor H4R with a Ki of 50 nM. 4-Methylhistamine has a >100-fold selectivity for the hH4R over the other histamine receptor subtypes. 4-Methylhistamine can potently activate the hH4R pEC50 = 7.4 . 4-Methylhistamine can be used for the researches of cancer, inflammation and immunology, such as lung cancer and skin inflammation.