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(4aS,8aR)-NPD-001
GENERAL CATALOGUE

(4aS,8aR)-NPD-001

HY-150025 · 50 mg

MedChemExpress · Cat: HY-150025

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medchemexpress.com/dnmt3a-in-2.html
Catalog No: HY-150025
CAS No: 2366272-43-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

4aS,8aR -NPD-001 is a potent and allosteric inhibitor of DNMT3A. 4aS,8aR -NPD-001 inhibits DNMT3A activity by disrupting protein-protein interactions. 4aS,8aR -NPD-001 induces apoptosis of acute myeloid leukemia AML cell lines. 4aS,8aR -NPD-001 induces differentiation of distinct AML cell lines including cells with mutated DNMT3A R882.

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