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?5?1 integrin agonist-1
GENERAL CATALOGUE

?5?1 integrin agonist-1

HY-139702 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-139702

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Catalog No: HY-139702
CAS No: 2756557-83-0
Category: Cytoskeleton
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

?5?1 integrin agonist-1 is an ?5?1 integrin agonist, with an EC50 of 1.5 nM. ?5?1 integrin agonist-1 inhabits ?4?1 integrin IC50 = 2.99 ?M in Jurkat/VCAM-1 adhesion assay?5?1 integrin agonist-1 induces concentration-dependent apoptosis and activates the caspase 3/7 pathway in ?5?1 integrin-expressing K562 cancer cells. ?5?1 integrin agonist-1 can be used for the study of cancer.

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