

HY-130502 · 5 mg
MedChemExpress · Cat: HY-130502
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medchemexpress.com/cholesterol-5beta-6beta-epoxide.htmlDescription
5?,6?-epoxycholestanol is an oxidative metabolite of cholesterol formed by free-radical and non-radical oxidation of cholesterol at the 5,6 double bond. Induces lactate dehydrogenase LDH release and apoptosis in macrophage-differentiated U937 cells. Cholesterol 5beta,6beta-epoxide has been found in human fatty streaks and advanced atherosclerotic lesions, but not in normal aortic tissue.