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5?,6?-epoxycholestanol
GENERAL CATALOGUE

5?,6?-epoxycholestanol

HY-130502 · 5 mg

MedChemExpress · Cat: HY-130502

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Catalog No: HY-130502
CAS No: 4025-59-6
Pack Size: 5 mg
Brand: MedChemExpress

Description

5?,6?-epoxycholestanol is an oxidative metabolite of cholesterol formed by free-radical and non-radical oxidation of cholesterol at the 5,6 double bond. Induces lactate dehydrogenase LDH release and apoptosis in macrophage-differentiated U937 cells. Cholesterol 5beta,6beta-epoxide has been found in human fatty streaks and advanced atherosclerotic lesions, but not in normal aortic tissue.

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