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5-Azacytidine, DNMT1 inhibitor
ab142744 · 250 mg
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Catalog No: ab142744
Category: Biochemicals
Pack Size: 250 mg
Brand: abcam
Description
MW 244.2 Da, Purity >98 %. Potent DNA methyltransferase 1 DNMT1 inhibitor IC50 = 0.2 muM . Incorporated into DNA, inhibits DNMT1 activity to induce DNA hypomethylation. Interferes with protein synthesis. Shows anti-metabolic and anti-cancer activities in vitro. Active in vivo. At high doses the compound can have effects on other DNA methyltransferases.
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