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5?-Azido-5?-deoxyadenosine
GENERAL CATALOGUE

5?-Azido-5?-deoxyadenosine

HY-154054 · 5 mg

MedChemExpress · Cat: HY-154054

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Catalog No: HY-154054
CAS No: 737-76-8
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress

Description

5?-Azido-5?-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. 5?-Azido-5?-deoxyadenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction CuAAc with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition SPAAC reactions with molecules containing DBCO or BCN groups.

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