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5-HT2B antagonist-2
GENERAL CATALOGUE

5-HT2B antagonist-2

HY-172258 · 50 mg

MedChemExpress · Cat: HY-172258

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Catalog No: HY-172258
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress

Description

5-HT2B antagonist-2 Compound 19c is a 5HT2B receptor antagonist with an IC50 of 1.09 nM. 5-HT2B antagonist-2 can downregulate the expression of fibrosis-related genes ?-SMA, Timp1, Col1a1, and Col3a1, and significantly reduce the deposition of fibrosis, thereby reducing the fibrotic area and inhibiting the fibrotic process in CCl4-induced liver fibrosis mouse models. 5-HT2B antagonist-2 can be used in the study of immune inflammatory-related diseases, particularly in the research of pulmonary fibrosis diseases.

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