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5-HT2CR agonist 1
GENERAL CATALOGUE

5-HT2CR agonist 1

HY-157425 · 50 mg

MedChemExpress · Cat: HY-157425

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Catalog No: HY-157425
CAS No: 1216074-15-5
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress

Description

5-HT2CR agonist 1 compound 8 , a 7-chloro analogue, is a selective 5-HT2CR partial agonist Emax=71.09 % with an EC50 value of 121.5 nM and no observed activity toward 5-HT2AR or 5-HT2BR. 5-HT2CR agonist 1 exhibits no recruitment activity for ?-arrestin and shows low inhibition of hERG at 10 ?M.

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