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5-HT7R antagonist 2
GENERAL CATALOGUE

5-HT7R antagonist 2

HY-163345 · 50 mg

MedChemExpress · Cat: HY-163345

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Catalog No: HY-163345
CAS No: 1448808-50-1
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress

Description

5-HT7R antagonist 2 compound 4h is a 5-HT7R antagonist that antagonizes the G protein and ?-arrestin signaling pathways, with a Ki of 67 nM, the IC50 values in cAMP and Tango tests were 2.59 ?M and 39.57 ?M, respectively. 5-HT7R antagonist 2 has an effect on neurogenesis and can reduce repetitive behaviors related to autism spectrum disorder ASD and restore neurogenesis of ASD impairment.

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