

HY-163345 · 50 mg
MedChemExpress · Cat: HY-163345
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medchemexpress.com/5-ht7r-antagonist-2.htmlDescription
5-HT7R antagonist 2 compound 4h is a 5-HT7R antagonist that antagonizes the G protein and ?-arrestin signaling pathways, with a Ki of 67 nM, the IC50 values in cAMP and Tango tests were 2.59 ?M and 39.57 ?M, respectively. 5-HT7R antagonist 2 has an effect on neurogenesis and can reduce repetitive behaviors related to autism spectrum disorder ASD and restore neurogenesis of ASD impairment.