GENERAL CATALOGUE
5-Iodo-indirubin-3'-monoxime
HY-111930 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-111930
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Catalog No: HY-111930
CAS No: 331467-03-9
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
5-Iodo-indirubin-3-monoxime is a potent GSK-3?, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively.