5-(N,N-Hexamethylene)-amiloride (Standard)

Description

5- N,N-Hexamethylene -amiloride Standard is the analytical standard of 5- N,N-Hexamethylene -amiloride. This product is intended for research and analytical applications. 5- N,N-Hexamethylene -amiloride Hexamethylene amiloride derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH pHi and induces apoptosis in leukemic cells. 5- N,N-Hexamethylene -amiloride Hexamethylene amiloride is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus MHV replication and human coronavirus 229E HCoV229E replication in cultured L929 cells with EC50s of 3.91 ?M and 1.34 ?M, respectively.