GENERAL CATALOGUE
5-O-Demethylnobiletin
HY-N1942 · 1 mg
MedChemExpress · Cat: HY-N1942
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Catalog No: HY-N1942
CAS No: 2174-59-6
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
5-O-Demethylnobiletin 5-Demethylnobiletin , a polymethoxyflavone isolated from Citrus jambhiri Lush., is a direct inhibition of 5-LOX IC50=0.1 ?M , without affecting the expression of COX-2. 5-O-Demethylnobiletin 5-Demethylnobiletin has anti-inflammatory activity, inhibits leukotriene B 4 LTB4 formation in rat neutrophils and elastase release in human neutrophils with an IC50 of 0.35 ?M.
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