

HY-168168 · 50 mg
MedChemExpress · Cat: HY-168168
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medchemexpress.com/5as-6r-6ar-mk-8666.htmlDescription
5aS,6R,6aR -MK-8666 is a selective GPR40 agonist with activity in promoting fatty acid-induced insulin secretion in pancreatic ? cells and intestinal enteroendocrine cells. 5aS,6R,6aR -MK-8666 has been studied for the inhibition of type 2 diabetes and has shown significant blood glucose lowering effects. Although 5aS,6R,6aR -MK-8666 is considered to have potential inhibitory advantages, its development was stopped in Phase I clinical trials due to liver safety issues.







