GENERAL CATALOGUE
(5Z,2E)-CU-3
HY-121638A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-121638A
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Manufacturer product page
medchemexpress.com/5z-2e-cu-3.htmlCatalog No: HY-121638A
CAS No: 1815598-71-0
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
5Z,2E -CU-3 is a potent and selective inhibitor against the ?-isozyme of DGK with an IC50 value of 0.6 ?M, competitively inhibits the affinity of DGK? for ATP with a Km value of 0.48 mM. 5Z,2E -CU-3 targets the catalytic region, but not the regulatory region of DGK?. 5Z,2E -CU-3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells.
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