6-Hydroxyflavone

Description

6-Hydroxyflavone is an orally effective flavonoid compound. 6-Hydroxyflavone can inhibit LPS HY-D1056 -induced NO production and has anti-inflammatory effects. 6-Hydroxyflavone promotes osteoblast differentiation by activating AKT, ERK 1/2 and JNK signaling pathways. 6-Hydroxyflavone has an inhibitory effect on bovine hemoglobin BHb glycosylation. 6-Hydroxyflavone has a kidney protective effect. In addition, 6-Hydroxyflavone enhances GABA-induced current through the Benzodiazepine sites of ?-aminobutyric acid GABAA receptors. 6-Hydroxyflavone shows a clear preference for ?2 - and ?3 - subtypes, which play an anti-anxiety role.