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7?,25-Dihydroxycholesterol
GENERAL CATALOGUE

7?,25-Dihydroxycholesterol

HY-113962 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-113962

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Catalog No: HY-113962
CAS No: 64907-22-8
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

7?, 25-dihydroxycholesterol 7?,25-OHC is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 GPR183 . 7?, 25-dihydroxycholesterol is highly potent at activating EBI2 EC50=140 pM; Kd=450 pM . 7?, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells.

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