

HY-112653 · 25 g
MedChemExpress · Cat: HY-112653
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medchemexpress.com/8_S_-HETE.htmlDescription
8 S -HETE 8 S -Hydroxyeicosatetraenoic acid is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 ?M. 8 S -HETE also activates PPAR? selectively at concentrations as low as 0.3 ?M. Stereochemical assignment of the S enantiomer is based on comparison of chiral HPLC retention times to published results.





