88 Tag Stable Y-LIZ DNA Polymerase-beta Knockout Mouse Embryonic Fibroblast Cell Line

Description

88 TAg Stable Y-LIZ DNA Polymerase-beta Knockout Mouse Embryonic Fibroblast Cell Line carries the lambda-LIZ transgene Y-LIZ , a shuttle vector which enables for mutation analysis. The 92 TAg is the wild type cell line to the polymerase beta knock out cells available at abm Cat. No. T3169, 92 TAg Stable Y-LIZ Wildtype Mouse Embryonic Fibroblast Cell Line . With the absence of the polymerase-beta, the cells are unable to efficiently repair 5dRP moiety as the cells lack the 5dRP lysase function causing the cells to become hypersensitive to alkylating agents.