GENERAL CATALOGUE
9-Hydroxyellipticin
HY-101775 · 50 mg
MedChemExpress · Cat: HY-101775
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Catalog No: HY-101775
CAS No: 51131-85-2
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
9-hydroxyellipticine is an inhibitor of Topo II and RyR, exhibiting high affinity for DNA with a Pka value of 9.8 at pH 7.4. It has antitumor, antioxidant, and catecholamine-releasing activities, with IC50 values of 1.6 ?M and 1.2 ?M for Hela S-3 and 293T cells, respectively. It also demonstrates anticancer effects in L1210 leukemia mice.
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