GENERAL CATALOGUE
A-381393
HY-116941 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-116941
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Catalog No: HY-116941
CAS No: 726174-00-1
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
A-381393 is a potent, selective, brain penetrate dopamine D4 receptor antagonist, with Kis of 1.5, 1.9 and 1.6 nM for human dopamine D4.4, D4.2, and D4.7 receptor, respectively, >2700-fold selectivity over D1, D2, D3 and D5 dopamine receptors. A-381393 shows moderate affinity for 5-HT2A Ki, 370 nM .
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